Preheat the oven to 375F and line a baking sheet with parchment paper.
Place salmon filets skin side down onto the baking sheet.
In a small bowl whisk together the juice of one lime, cumin, honey, salt, olive oil, chili powder, garlic powder and a pinch of ground pepper until well combined. Save 1 tbsp of the sauce and set aside
Brush or drizzle the chili lime mixture over the salmon to coat it.
Once the oven is preheated, bake salmon until it easily flakes with a fork and an instant read thermometer inserted into the salmon reads 140-145, about 12-18 minutes (cook times will vary depending on thickness of the salmon).
While the salmon is cooking, make the mango salsa by adding all of the ingredients to a medium bowl and stir. Set aside until the salmon is ready.
Once the salmon is done to your desired temperature, drizzle the remaining chili lime sauce over the salmon and serve with extra lime wedges and your favorite sides.
Notes
If you prefer to grill the salmon, heat the grill to 350-375F and make sure to oil the grill well so the salmon doesn't stick (I like to use avocado oil as it has a higher smoke point). Brush both pieces of salmon to coat well with the sauce (save the rest). Grill for about 5-7 minutes on the first side, brush with more of the sauce and then grill 3-5 minutes more on the second side or until cooked through to your desired temperature. Finish the salmon with leftover sauce and top with the mango salsa.
The mango salsa is optional but it adds a burst of fresh flavour! Alternatively, you could replace the mango with 1-2 avocados and make a delicious avocado salsa to top the salmon instead.
How can I tell if my salmon is cooked? If you don't have a thermometer the easiest way to tell if your salmon is finished cooking is to press down gently on the top of the thickest part of your salmon filet with a fork; the salmon should flake easily meaning it should separate easily. If you have a thermometer, measure in the thickest part of the salmon. You're looking for 125-130 degrees F for medium cooked salmon and to ensure full safety most seafood should be cooked to 145F.